Hormone Therapy - Men Pregnenolone Another hormone to consider supplementing is pregnenolone.  The body makes it from cholesterol, and uses it to make DHEA and all of the sex-related  hormones.  Its benefits include an ability to improve memory and other mental functions, and increase muscle mass.  Similarly, as with DHEA, a topical formulation can produce higher blood levels.  Since this important precursor hormone is  made from cholesterol, people who take drugs to lower their cholesterol levels should especially consider pregnenolone supplementation

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